Center for Brain & Disease Research
CBD in a nutshell
Science Directors: Patrik Verstreken & Joris de Wit
Neuronal and neurodegenerative disorders affect millions of people worldwide. For most of these diseases, there are no cures, only symptomatic treatments. At CBD, we are working hard to understand the basis of these diseases with the hope to find better treatment options. We explore new molecular mechanisms in the context of Alzheimer’s disease, Parkinson’s disease, ALS and dystonia. Together with our tech transfer team, we translate our findings into therapeutic avenues. The brain poses specific challenges for drug delivery as it is shielded by a blood-brain barrier, which is why we are also developing tools to ensure that the drugs we develop can reach their target.
Labs
Function
Lab of proteolytic mechanisms mediating neurodegeneration
Impact on society
Targeting drugs to the brain
Developing a platform to find nanobody constructs that can cross the blood-brain barrier, as a way of treating brain diseases in the blood-brain-barrier (BBB) project.
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